Project Outputs

Our project receives funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 874758. Have a look at the list of publications of the project which will be updated during the whole life of the Consortium (2020-2024). Recent publications are at the top of the list:


2025

Bocchi R, Thorwirth M, Simon-Ebert T, Koupourtidou C, Clavreul S, Kolf K, Della Vecchia P, Bottes S, Jessberger S, Zhou J, Wani G, Pilz GA, Ninkovic J, Buffo A, Sirko S, Götz M, Fischer-Sternjak J.
Astrocyte heterogeneity reveals region-specific astrogenesis in the white matter.
Nat Neurosci. 2025 Feb 24. doi: 10.1038/s41593-025-01878-6. Epub ahead of print.

Cattaneo E, Besusso D.
Stem Cell Revolutions: An alliance for Parkinson's disease driven by European Commission consortia.
Pharmacol Res. 2025 Feb;212:107569. doi: 10.1016/j.phrs.2024.107569.

Natarajan P, Koupourtidou C, de Resseguier T, Thorwirth M, Bocchi R, Fischer-Sternjak J, Gleiss S, Rodrigues D, Myoga MH, Ninkovic J, Masserdotti G, Götz M.
Single Cell Deletion of the Transcription Factors Trps1 and Sox9 in Astrocytes Reveals Novel Functions in the Adult Cerebral Cortex.
Glia. 2025 Apr;73(4):737-758. doi: 10.1002/glia.24645. Epub 2024 Nov 28.


2024

Barker RA, Björklund A, Parmar M.
The history and status of dopamine cell therapies for Parkinson's disease.
Bioessays. 2024 Dec;46(12):e2400118. doi: 10.1002/bies.202400118. Epub 2024 Jul 26.

Berg LJ, Lee CK, Matsumura H, Leinhaas A, Konang R, Shaib AH, Royero P, Schlee J, Sheng C, Beck H, Schwarz MK, Brose N, Rhee JS, Brüstle O.
Human neural stem cells directly programmed from peripheral blood show functional integration into the adult mouse brain.
Stem Cell Res Ther. 2024 Dec 20;15(1):488. doi: 10.1186/s13287-024-04110-7.

Cattaneo E, Barker RA.
Brain cholesterol therapy for Huntington's disease - Does it make sense?
Clin Transl Med. 2024 Jul;14(7):e1746. doi: 10.1002/ctm2.1746.

Christiansen JR, Kirkeby A.
Clinical translation of pluripotent stem cell-based therapies: successes and challenges.
Development. 2024 Apr 1;151(7):dev202067. doi: 10.1242/dev.202067. Epub 2024 Apr 2.

Fiorenzano A, Storm P, Sozzi E, Bruzelius A, Corsi S, Kajtez J, Mudannayake J, Nelander J, Mattsson B, Åkerblom M, Björklund T, Björklund A, Parmar M.
TARGET-seq: Linking single-cell transcriptomics of human dopaminergic neurons with their target specificity.
Proc Natl Acad Sci U S A. 2024 Nov 19;121(47):e2410331121. doi: 10.1073/pnas.2410331121. Epub 2024 Nov 14.

Fogli M, Nato G, Greulich P, Pinto J, Ribodino M, Valsania G, Peretto P, Buffo A, Luzzati F.
Dynamic spatiotemporal activation of a pervasive neurogenic competence in striatal astrocytes supports continuous neurogenesis following injury.
Stem Cell Reports. 2024 Oct 8;19(10):1432-1450. doi: 10.1016/j.stemcr.2024.08.006. Epub 2024 Sep 19.

Knöbel S, Bosio A.
Scaling of cell and gene therapies to population.
Handb Clin Neurol. 2024;205:145-154. doi: 10.1016/B978-0-323-90120-8.00012-5.

Kojima R, Paslawski W, Lyu G, Arenas E, Zhang X, Svenningsson P.
Secretome Analyses Identify FKBP4 as a GBA1-Associated Protein in CSF and iPS Cells from Parkinson's Disease Patients with GBA1 Mutations.
Int J Mol Sci. 2024 Jan 4;25(1):683. doi: 10.3390/ijms25010683.

Libé-Philippot B, Iwata R, Recupero AJ, Wierda K, Bernal Garcia S, Hammond L, van Benthem A, Limame R, Ditkowska M, Beckers S, Gaspariunaite V, Peze-Heidsieck E, Remans D, Charrier C, Theys T, Polleux F, Vanderhaeghen P.
Synaptic neoteny of human cortical neurons requires species-specific balancing of SRGAP2-SYNGAP1 cross-inhibition.
Neuron. 2024 Nov 6;112(21):3602-3617.e9. doi: 10.1016/j.neuron.2024.08.021. Epub 2024 Oct 14.

Pereira A, Diwakar J, Masserdotti G, Beşkardeş S, Simon T, So Y, Martín-Loarte L, Bergemann F, Vasan L, Schauer T, Danese A, Bocchi R, Colomé-Tatché M, Schuurmans C, Philpott A, Straub T, Bonev B, Götz M.
Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1.
Nat Neurosci. 2024 Jul;27(7):1260-1273. doi: 10.1038/s41593-024-01677-5. Epub 2024 Jul 2.

Puglisi M, Lao CL, Wani G, Masserdotti G, Bocchi R, Götz M.
Comparing Viral Vectors and Fate Mapping Approaches for Astrocyte-to-Neuron Reprogramming in the Injured Mouse Cerebral Cortex.
Cells. 2024 Aug 23;13(17):1408. doi: 10.3390/cells13171408.

Rifes P, Kajtez J, Christiansen JR, Schörling A, Rathore GS, Wolf DA, Heuer A, Kirkeby A.
Forced LMX1A expression induces dorsal neural fates and disrupts patterning of human embryonic stem cells into ventral midbrain dopaminergic neurons.
Stem Cell Reports. 2024 Jun 11;19(6):830-838. doi: 10.1016/j.stemcr.2024.04.010.

Sif Ásgrímsdóttir E, Arenas E.
Generation of a fluorescent hESC reporter line (Kle033-A-1) for the isolation of distinct midbrain progenitor cell types.
Stem Cell Res. 2024 Dec;81:103523. doi: 10.1016/j.scr.2024.103523.

Sonsalla G, Malpartida AB, Riedemann T, Gusic M, Rusha E, Bulli G, Najas S, Janjic A, Hersbach BA, Smialowski P, Drukker M, Enard W, Prehn JHM, Prokisch H, Götz M, Masserdotti G.
Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprogramming hurdle.
Neuron. 2024 Apr 3;112(7):1117-1132.e9. doi: 10.1016/j.neuron.2023.12.020. Epub 2024 Jan 23.

Storm P, Zhang Y, Nilsson F, Fiorenzano A, Krausse N, Åkerblom M, Davidsson M, Yuan J, Kirkeby A, Björklund T, Parmar M.
Lineage tracing of stem cell-derived dopamine grafts in a Parkinson's model reveals shared origin of all graft-derived cells.
Sci Adv. 2024 Oct 18;10(42):eadn3057. doi: 10.1126/sciadv.adn3057. Epub 2024 Oct 18.

Vermaercke B, Iwata R, Wierda K, Boubakar L, Rodriguez P, Ditkowska M, Bonin V, Vanderhaeghen P.
SYNGAP1 deficiency disrupts synaptic neoteny in xenotransplanted human cortical neurons in vivo.
Neuron. 2024 Sep 25;112(18):3058-3068.e8. doi: 10.1016/j.neuron.2024.07.007. Epub 2024 Aug 6.

Walsh RM, Luongo R, Giacomelli E, Ciceri G, Rittenhouse C, Verrillo A, Galimberti M, Bocchi VD, Wu Y, Xu N, Mosole S, Muller J, Vezzoli E, Jungverdorben J, Zhou T, Barker RA, Cattaneo E, Studer L, Baggiolini A.
Generation of human cerebral organoids with a structured outer subventricular zone.
Cell Rep. 2024 Apr 23;43(4):114031. doi: 10.1016/j.celrep.2024.114031. Epub 2024 Apr 6.


2023
 
Avallone, M., Pardo, J., Mergiya, T. F., Rájová, J., Räsänen, A., Davidsson, M., Åkerblom, M., Quintino, L., Kumar, D., Bramham, C. R., & Björklund, T. (2023).
Visualizing Arc protein dynamics and localization in the mammalian brain using AAV-mediated in situ gene labeling
Frontiers in molecular neuroscience16, 1140785.
 
Berg, L. J., & Brüstle, O. (2023).
Stem cell programming - prospects for perinatal medicine
Journal of perinatal medicine51(6), 730–736.
 
Braun, E., Danan-Gotthold, M., Borm, L. E., Lee, K. W., Vinsland, E., Lönnerberg, P., Hu, L., Li, X., He, X., Andrusivová, Ž., Lundeberg, J., Barker, R. A., Arenas, E., Sundström, E., & Linnarsson, S. (2023).
Comprehensive cell atlas of the first-trimester developing human brain
Science (New York, N.Y.)382(6667), eadf1226.
 
Giacomoni, J., Habekost, M., Cepeda-Prado, E., Mattsson, B., Ottosson, D. R., Parmar, M., & Kajtez, J. (2023).
Protocol for optical clearing and imaging of fluorescently labeled ex vivo rat brain slices
STAR protocols4(1), 102041.
 
Grimaldi P., Lorenzati M., Ribodino M., Signorino E., Buffo A., & Berchialla P. (2023).
Predicting Astrocytic Nuclear Morphology with Machine Learning: A Tree Ensemble Classifier Study.
Applied Sciences, 13(7), 4289.
 
Kirkeby, A., Nelander, J., Hoban, D. B., Rogelius, N., Bjartmarz, H., Novo Nordisk Cell Therapy R&D, Storm, P., Fiorenzano, A., Adler, A. F., Vale, S., Mudannayake, J., Zhang, Y., Cardoso, T., Mattsson, B., Landau, A. M., Glud, A. N., Sørensen, J. C., Lillethorup, T. P., Lowdell, M., Carvalho, C., Bain O., van Vliet T., Lindvall O., Björklund A., Harry B., Cutting E., Widner H., Paul G., Barker R. A., Parmar, M. (2023).
Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PD
Cell stem cell30(10), 1299–1314.e9.
 
Libé-Philippot, B., Lejeune, A., Wierda, K., Louros, N., Erkol, E., Vlaeminck, I., Beckers, S., Gaspariunaite, V., Bilheu, A., Konstantoulea, K., Nyitrai, H., De Vleeschouwer, M., Vennekens, K. M., Vidal, N., Bird, T. W., Soto, D. C., Jaspers, T., Dewilde, M., Dennis, M. Y., Rousseau, F., Comoletti D., Schymkowitz J., Theys T., de Wit J., Vanderhaeghen, P. (2023).
LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons. 
Cell186(26), 5766–5783.e25.
 
Nishimura, K., Ásgrímsdóttir, E. S., Yang, S., & Arenas, E. (2023).
A protocol for the differentiation of human embryonic stem cells into midbrain dopaminergic neurons. 
STAR protocols4(3), 102355. Advance online publication.
 
Nishimura, K., Yang, S., Lee, K. W., Ásgrímsdóttir, E. S., Nikouei, K., Paslawski, W., Gnodde, S., Lyu, G., Hu, L., Saltó, C., Svenningsson, P., Hjerling-Leffler, J., Linnarsson, S., & Arenas, E. (2023).
Single-cell transcriptomics reveals correct developmental dynamics and high-quality midbrain cell types by improved hESC differentiation. 
Stem cell reports18(1), 337–353.
 
Rájová, J., Davidsson, M., Avallone, M., Hartnor, M., Aldrin-Kirk, P., Cardoso, T., Nolbrant, S., Mollbrink, A., Storm, P., Heuer, A., Parmar, M., & Björklund, T. (2023).
Deconvolution of spatial sequencing provides accurate characterization of hESC-derived DA transplants in vivo.
Molecular therapy. Methods & clinical development, 29, 381–394.
 
Reumann, D., Krauditsch, C., Novatchkova, M., Sozzi, E., Wong, S. N., Zabolocki, M., Priouret, M., Doleschall, B., Ritzau-Reid, K. I., Piber, M., Morassut, I., Fieseler, C., Fiorenzano, A., Stevens, M. M., Zimmer, M., Bardy, C., Parmar, M., & Knoblich, J. A. (2023).
In vitro modeling of the human dopaminergic system using spatially arranged ventral midbrain-striatum-cortex assembloids. 
Nature methods20(12), 2034–2047.
 
Rifes, P., Isaksson, M., Rusimbi, C., Ramón Santonja, A., Nelander, J., Laurell, T., & Kirkeby, A. (2023).
Identifying secreted biomarkers of dopaminergic ventral midbrain progenitor cells.
Stem cell research & therapy14(1), 354.
 
Schellino, R., Besusso, D., Parolisi, R., Gómez-González, G. B., Dallere, S., Scaramuzza, L., Ribodino, M., Campus, I., Conforti, P., Parmar, M., Boido, M., Cattaneo, E., & Buffo, A. (2023).
hESC-derived striatal progenitors grafted into a Huntington's disease rat model support long-term functional motor recovery by differentiating, self-organizing and connecting into the lesioned striatum. 
Stem cell research & therapy14(1), 189.
 
Siletti, K., Hodge, R., Mossi Albiach, A., Lee, K. W., Ding, S. L., Hu, L., Lönnerberg, P., Bakken, T., Casper, T., Clark, M., Dee, N., Gloe, J., Hirschstein, D., Shapovalova, N. V., Keene, C. D., Nyhus, J., Tung, H., Yanny, A. M., Arenas, E., Lein, E. S., Linnarsson, S. (2023).
Transcriptomic diversity of cell types across the adult human brain. 
Science (New York, N.Y.)382(6667), eadd7046.
 
Sirko, S., Schichor, C., Della Vecchia, P., Metzger, F., Sonsalla, G., Simon, T., Bürkle, M., Kalpazidou, S., Ninkovic, J., Masserdotti, G., Sauniere, J. F., Iacobelli, V., Iacobelli, S., Delbridge, C., Hauck, S. M., Tonn, J. C., & Götz, M. (2023).
Injury-specific factors in the cerebrospinal fluid regulate astrocyte plasticity in the human brain. 
Nature medicine29(12), 3149–3161.
 
Walsh, R., Giacomelli, E., Ciceri, G., Rittenhouse, C., Galimberti, M., Wu, Y., Muller, J., Vezzoli, E., Jungverdorben, J., Zhou, T., Barker, R. A., Cattaneo, E., Studer, L., & Baggiolini, A. (2023).
Generation of human cerebral organoids with a structured outer subventricular zone. 
bioRxiv: the preprint server for biology, 2023.02.17.528906.


 2022
 
Bauer A, Puglisi M, Nagl D, Schick JA, Werner T, Klingl A, El Andari J, Hornung V, Kessler H, Götz M, Grimm D, Brack-Werner R.
Molecular Signature of Astrocytes for Gene Delivery by the Synthetic Adeno-Associated Viral Vector rAAV9P1.
Adv Sci (Weinh). 2022 May;9(16):e2104979. doi: 10.1002/advs.202104979. Epub 2022 Apr 10. PMID: 35398994; PMCID: PMC9165502.
 
Bocchi R, Masserdotti G, Götz M.
Direct neuronal reprogramming: Fast forward from new concepts toward therapeutic approaches.
Neuron. 2022 Feb 2;110(3):366-393. doi: 10.1016/j.neuron.2021.11.023. Epub 2021 Dec 18. PMID: 34921778.
 
Conforti P, Bocchi VD, Campus I, Scaramuzza L, Galimberti M, Lischetti T, Talpo F, Pedrazzoli M, Murgia A, Ferrari I, Cordiglieri C, Fasciani A, Arenas E, Felsenfeld D, Biella G, Besusso D, Cattaneo E.
In vitro-derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution.
Cell Rep Methods. 2022 Dec 19;2(12):100367. doi: 10.1016/j.crmeth.2022.100367. PMID: 36590694; PMCID: PMC9795363.
 
Cruz-Santos M, Cardo LF, Li M.
A Novel LHX6 Reporter Cell Line for Tracking Human iPSC-Derived Cortical Interneurons.
Cells. 2022 Mar 1;11(5):853. doi: 10.3390/cells11050853. PMID: 35269475; PMCID: PMC8909769.
 
Hersbach BA, Fischer DS, Masserdotti G, Deeksha, Mojžišová K, Waltzhöni T, Rodriguez-Terrones D, Heinig M, Theis FJ, Götz M, Stricker SH.
Probing cell identity hierarchies by fate titration and collision during direct reprogramming.
Mol Syst Biol. 2022 Sep;18(9):e11129. doi: 10.15252/msb.202211129. PMID: 36106915; PMCID: PMC9476893.
 
Flitsch LJ, Börner K, Stüllein C, Ziegler S, Sonntag-Buck V, Wiedtke E, Semkova V, Au Yeung SWC, Schlee J, Hajo M, Mathews M, Ludwig BS, Kossatz S, Kessler H, Grimm D, Brüstle O.
Identification of adeno-associated virus variants for gene transfer into human neural cell types by parallel capsid screening.
Sci Rep. 2022 May 19;12(1):8356. doi: 10.1038/s41598-022-12404-0. PMID: 35589936; PMCID: PMC9120183.
 
Radtke F, Palladino VS, McNeill RV, Chiocchetti AG, Haslinger D, Leyh M, Gersic D, Frank M, Grünewald L, Klebe S, Brüstle O, Günther K, Edenhofer F, Kranz TM, Reif A, Kittel-Schneider S.
ADHD-associated PARK2 copy number variants: A pilot study on gene expression and effects of supplementary deprivation in patient-derived cell lines.
Am J Med Genet B Neuropsychiatr Genet. 2022 Oct;189(7-8):257-270. doi: 10.1002/ajmg.b.32918. Epub 2022 Aug 16. PMID: 35971782.
 
Rodriguez-Gatica JE, Iefremova V, Sokhranyaeva L, Au Yeung SWC, Breitkreuz Y, Brüstle O, Schwarz MK, Kubitscheck U.
Imaging three-dimensional brain organoid architecture from meso- to nanoscale across development.
Development. 2022 Oct 15;149(20):dev200439. doi: 10.1242/dev.200439. Epub 2022 Aug 5. PMID: 35899577.
 
Sozzi E, Nilsson F, Kajtez J, Parmar M, Fiorenzano A.
Generation of Human Ventral Midbrain Organoids Derived from Pluripotent Stem Cells.
Curr Protoc. 2022 Sep;2(9):e555. doi: 10.1002/cpz1.555. PMID: 36121202.
 
Sozzi E, Kajtez J, Bruzelius A, Wesseler MF, Nilsson F, Birtele M, Larsen NB, Ottosson DR, Storm P, Parmar M, Fiorenzano A.
Silk scaffolding drives self-assembly of functional and mature human brain organoids.
Front Cell Dev Biol. 2022 Oct 14;10:1023279. doi: 10.3389/fcell.2022.1023279. PMID: 36313550; PMCID: PMC9614032.
 
Wen J, Peitz M, Brüstle O.
A defined human-specific platform for modeling neuronal network stimulation in vitro and in silico.
J Neurosci Methods. 2022 May 1;373:109562. doi: 10.1016/j.jneumeth.2022.109562. Epub 2022 Mar 12. PMID: 35292305.
 
 
2021
 
Ahmed M, Owens MJS, Toledo EM, Arenas E, Bradley M, Ffrench-Constant C.
Combinatorial ECM Arrays Identify Cooperative Roles for Matricellular Proteins in Enhancing the Generation of TH+ Neurons From Human Pluripotent Cells.
Front Cell Dev Biol. 2021 Dec 1;9:755406. doi: 10.3389/fcell.2021.755406. PMID: 34926447; PMCID: PMC8672163.
 
Aldrin-Kirk P, Åkerblom M, Cardoso T, Nolbrant S, Adler AF, Liu X, Heuer A, Davidsson M, Parmar M, Björklund T.
A novel two-factor monosynaptic TRIO tracing method for assessment of circuit integration of hESC-derived dopamine transplants.
Stem Cell Reports. 2022 Jan 11;17(1):159-172. doi: 10.1016/j.stemcr.2021.11.014. Epub 2021 Dec 30. PMID: 34971563; PMCID: PMC8758947.
 
Bocchi VD, Conforti P, Vezzoli E, Besusso D, Cappadona C, Lischetti T, Galimberti M, Ranzani V, Bonnal RJP, De Simone M, Rossetti G, He X, Kamimoto K, Espuny-Camacho I, Faedo A, Gervasoni F, Vuono R, Morris SA, Chen J, Felsenfeld D, Pavesi G, Barker RA, Pagani M, Cattaneo E.
The coding and long noncoding single-cell atlas of the developing human fetal striatum.
Science. 2021 May 7;372(6542):eabf5759. doi: 10.1126/science.abf5759. PMID: 33958447.
 
Cruz MS, Li M.
Identification of TGFβ signaling as a regulator of interneuron neurogenesis in a human pluripotent stem cell model.
Neuronal Signal. 2021 Dec 7;5(4):NS20210020. doi: 10.1042/NS20210020. PMID: 34956651; PMCID: PMC8661503.
 
Fiorenzano A, Sozzi E, Birtele M, Kajtez J, Giacomoni J, Nilsson F, Bruzelius A, Sharma Y, Zhang Y, Mattsson B, Emnéus J, Ottosson DR, Storm P, Parmar M.
Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids.
Nat Commun. 2021 Dec 15;12(1):7302. doi: 10.1038/s41467-021-27464-5. Erratum in: Nat Commun. 2022 Jun 8;13(1):3312. PMID: 34911939; PMCID: PMC8674361.
 
Kempf J, Knelles K, Hersbach BA, Petrik D, Riedemann T, Bednarova V, Janjic A, Simon-Ebert T, Enard W, Smialowski P, Götz M, Masserdotti G.
Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2.
Cell Rep. 2021 Jul 20;36(3):109409. doi: 10.1016/j.celrep.2021.109409. Erratum in: Cell Rep. 2021 Aug 17;36(7):109571. PMID: 34289357; PMCID: PMC8316252.
 
Ohlig S, Clavreul S, Thorwirth M, Simon-Ebert T, Bocchi R, Ulbricht S, Kannayian N, Rossner M, Sirko S, Smialowski P, Fischer-Sternjak J, Götz M.
Molecular diversity of diencephalic astrocytes reveals adult astrogenesis regulated by Smad4.
EMBO J. 2021 Nov 2;40(21):e107532. doi: 10.15252/embj.2020107532. Epub 2021 Sep 22. PMID: 34549820; PMCID: PMC8561644.
 
Parmar M, Björklund A, Björklund T.
In vivo conversion of dopamine neurons in mouse models of Parkinson's disease - a future approach for regenerative therapy?
Curr Opin Genet Dev. 2021 Oct;70:76-82. doi: 10.1016/j.gde.2021.06.002. Epub 2021 Jun 24. PMID: 34175529.
 
Qarin S, Howlett SK, Jones JL, Barker RA.
The immunogenicity of midbrain dopaminergic neurons and the implications for neural grafting trials in Parkinson's disease.
Neuronal Signal. 2021 Sep 13;5(3):NS20200083. doi: 10.1042/NS20200083. PMID: 34552761; PMCID: PMC8438115.
 
Rivetti di Val Cervo P, Besusso D, Conforti P, Cattaneo E.
hiPSCs for predictive modelling of neurodegenerative diseases: dreaming the possible.
Nat Rev Neurol. 2021 Jun;17(6):381-392. doi: 10.1038/s41582-021-00465-0. Epub 2021 Mar 3. PMID: 33658662; PMCID: PMC7928200.
 
2020
 
Arenas E.
Method to combat Parkinson's disease by astrocyte-to-neuron conversion.
Nature. 2020 Jun;582(7813):489-490. doi: 10.1038/d41586-020-01817-4. PMID: 32581373.
 
Ásgrímsdóttir ES, Arenas E.
Midbrain Dopaminergic Neuron Development at the Single Cell Level: In vivo and in Stem Cells.
Front Cell Dev Biol. 2020 Jun 25;8:463. doi: 10.3389/fcell.2020.00463. PMID: 32733875; PMCID: PMC7357704.
 
Besusso D, Cossu A, Mohamed A, Cernigoj M, Codega P, Galimberti M, Campus I, Conforti P, Cattaneo E.
A CRISPR-strategy for the generation of a detectable fluorescent hESC reporter line (WAe009-A-37) for the subpallial determinant GSX2.
Stem Cell Res. 2020 Dec;49:102016. doi: 10.1016/j.scr.2020.102016. Epub 2020 Oct 1. PMID: 33039807.
 
Besusso D, Schellino R, Boido M, Belloli S, Parolisi R, Conforti P, Faedo A, Cernigoj M, Campus I, Laporta A, Bocchi VD, Murtaj V, Parmar M, Spaiardi P, Talpo F, Maniezzi C, Toselli MG, Biella G, Moresco RM, Vercelli A, Buffo A, Cattaneo E.
Stem Cell-Derived Human Striatal Progenitors Innervate Striatal Targets and Alleviate Sensorimotor Deficit in a Rat Model of Huntington Disease.
Stem Cell Reports. 2020 May 12;14(5):876-891. doi: 10.1016/j.stemcr.2020.03.018. Epub 2020 Apr 16. PMID: 32302555; PMCID: PMC7220987.

Palladino VS, Chiocchetti AG, Frank L, Haslinger D, McNeill R, Radtke F, Till A, Haupt S, Brüstle O, Günther K, Edenhofer F, Hoffmann P, Reif A, Kittel-Schneider S.
Energy Metabolism Disturbances in Cell Models of PARK2 CNV Carriers with ADHD.
J Clin Med. 2020 Dec 18;9(12):4092. doi: 10.3390/jcm9124092. PMID: 33353000; PMCID: PMC7766864.